Q1. Knowledge and understanding:
At the end of the course the student must demonstrate knowledge of the fundamental aspects of anamnestic order and clinical expression, associated with the development of immune-mediated diseases of an autoimmune connective tissue order, systemic autoinflammatory diseases, genetic or acquired, immunosuppressive diseases and physical alterations associated with allergic pathologies.
Q2. Ability to apply knowledge and understanding:
at the end of the course the student must be able to apply the knowledge acquired in point D1 to hypothesize the presence and identify at the onset immune-mediated diseases and understand their development and consequences as well as complications. The student will have to demonstrate that he can associate the disorders described with the findings in the field of physical semeiological evaluation.
Q3. Making judgments:
at the end of the course the student should have sufficient means to judge the onset and progression scenarios of the immune-mediated diseases referred to in the program
Q4. Communication skills:
at the end of the course the student must be able to clearly explain the concepts acquired in point D1, using the appropriate terminology
Q5. Learning ability:
at the end of the course the student must be able to independently deepen the topics covered, furthermore he must be able to transfer the concepts acquired in the context of the subsequent courses to start clinical practice

appropriate information and terminology acquired in the previous courses of biochemistry, human anatomy, general pathology, general immunology, physiology

- systemic autoinflammatory diseases
- systemic autoimmune rheumatic diseases
- organ-system autoimmune diseases (auto-antibody reactivity aspects)
- notes on primary type immune deficiencies
- secondary type immune response deficit
- allergy-mediated immunopathies

Oxford Handbook of Clinical Immunology and Allergy
Editor : Gavin Spickett
Oxford University Press
2019

- systemic auto-inflammatory diseases of genetic type with infantile expression or with expression in later life to adult (such as adult Still Disease, syndr from macrophage activation, IgG4 related disease, juvenile chronic arthritis with systemic expression).
- Autoimmune Connective Diseases (Systemic Lupus Erythematosus, Sjogren's Syndrome, Polymyositis, Systemic Sclerosis, Antiphospholipid Antibody Syndrome, Undifferentiated Connective Diseases)
- systemic vasculitides
- congenital and acquired immunodeficiency
- allergic-type diseases (clinical expressions and diagnosis of IgE-mediated and non-IgE-mediated allergic diseases, food, skin, respiratory, drug-related)
- hymenoptera venom allergies
- systemic anaphylactic reaction and pseudo-allergic systemic reactions
- urticaria and angioedema.

- frontal lessons
- didactic material transmitted electronically (slides)
- availability for clarification or in-depth meetings at the request of the student

- written exam and subsequent oral exam
-in the written questionnaire, 10 questions per exam session, multiple choice, each worth 1 point.
If the sufficiency of written answers is exceeded (6/10 points acquired) passage to the oral phase lasting at least 30 minutes (comment on clinical scenarios and medical pathophysiology
Final grade expressed out of thirty. Minimum positive vote corresponding to 18 out of 30.
The evaluation criteria are based on the aspects described in the learning objectives section

This course explores topics closely related to one or more goals of the United Nations 2030 Agenda for Sustainable Development (SDGs)