KNOWLEDGE AND UNDERSTANDING: students should acquire knowledge on cell and molecular biology. APPLYING KNOWLEDGE AND UNDERSTANDING: students should be able to apply their knowledge on cell and molecular biology to understand and explain the organization and functions of the cell, the processes of replication and expression of genetic information and protein synthesis. MAKING JUDGEMENTS: students should be able to use the acquired knowledge to develop a personal judgment and decision making approach and an independent critical view of the themes proposed in the course. COMMUNICATION SKILLS: by the end of the course, students will be able to use a proper and appropriate technical-professional terminology to effectively communicate about cell and molecular biology. LEARNING SKILLS: by the end of the course, students will prove to know the main themes of the course and to be able to prepare the Profit Exam by searching for availability, analyzing the contents and assessing the applicability of a guideline, based on the content of the lessons, and the sources suggested.

There are no specific requirements. The students should have knowledge of the basic principles of chemistry and physics.

APPLIED BIOLOGY The aim of this course is to deal a general overview on the bases of cell and molecular biology, the knowledge of the processes of replication and expression of genetic information and the organization and functions of the cell DETAILED PROGRAM • General overview on the bases of life and on biological macromolecules • The cell, the working unit of life: prokaryotes, eukaryotes and viruses • Cell structure and function of organelles. • Cytoskeleton: microtubules, intermediate filaments and microfilaments. • Cell membranes: structure, functions, and processes of membrane transport • Extracellular matrix, adhesion proteins, cellular recognition. • Cell cycle, Mitosis and Meiosis and regulation of cell cycle. • DNA e RNA, duplication, repair and transcription • The genetic code, structure and function of ribosomes and protein synthesis. • Cellular response to environment: Signal transduction pathways, signaling molecules and their receptors.

1) Biologia e genetica. C. Donati, M. Stefani, N. Taddei. ZANICHELLI 2019. 2) Fondamenti di Biologia. E. P. Solomon, C. E. Martin, D. W. Martin, L. R. Berg. EDISES 2022. 3) Basi molecolari e cellulari della vita. A. Bevilacqua, P. Chieffi, L. Speranza, S. Canterini, M. Pesce, M. Montorsi. PICCIN 2020.

APPLIED BIOLOGY The aim of this course is to deal a general overview on the bases of cell and molecular biology, the knowledge of the processes of replication and expression of genetic information and the organization and functions of the cell DETAILED PROGRAM • General overview on the bases of life and on biological macromolecules • The cell, the working unit of life: prokaryotes, eukaryotes and viruses • Cell structure and function of organelles. • Cytoskeleton: microtubules, intermediate filaments and microfilaments. • Cell membranes: structure, functions, and processes of membrane transport • Extracellular matrix, adhesion proteins, cellular recognition. • Cell cycle, Mitosis and Meiosis and regulation of cell cycle. • DNA e RNA, duplication, repair and transcription • The genetic code, structure and function of ribosomes and protein synthesis. • Cellular response to environment: Signal transduction pathways, signaling molecules and their receptors.

Lectures.

The material presented and discussed in the class will be available on the MS Teams platform.

Written test including 15 multiple-choice questions and 1 open question. The students will complete the test in 1 hou. Scores will be assigned as follows: Multiple-choice questions are included in two goups: One group of 6 questions on fundamental topics. Each correct answer will score 3 points. Incorrect/missing answers will score 0 points. One group of 9 questions on specific topics. Each correct answer will score 1 point. Incorrect/missing answers will score 0 points. Answer to open question will score 3 points if the student demonstrates excellent and complete knowledge of the topic and also ability to answer in using proper terminology and in a concise way. 1-2 points is the answer is incomplete, partially correct, presented in a unclear way and/or using improper terminology. 0 points if the students shows insufficient knowledge or does not answer to the question.