The main objective of the course is to provide students with the basic knowledge and an introduction of organic materials and organic-inorganic hybrid materials relevant to materials science and biology and medicine.
Knowledge and understanding: Knowledge of weak bonds involved in the formation of organic materials. Understanding and application of the concept of self-assembling. Knowledge of the properties of materials in the nanometer scale. Understanding the structure-property relationship. Understanding how to change the properties of the material.
Ability to apply knowledge and understanding. The acquisition of this capacity is stimulated by the teacher during classroom lectures, critically presenting numerous applications; in the discussion of scientific works selected by the teacher; in preparation for the final exam.
Making judgments. The autonomy of judgment is developed during the lessons in the classroom and through the preparation for the exam, which requires the individual re-elaboration and assimilation of the material presented in class. During the lessons, evaluation and selected exercises are proposed and discussed concerning the most appropriate strategy for the preparation of a material or for the selection of a material for a specific application.
Communication skills. During the lessons the students are called to interact with the teacher also to acquire language properties and learn how to correctly express the concepts presented by the teacher. The student must also present a scientific work orally with the aid of a video projector presentation in a concise and effective manner.
Learning ability. the ability to learn is stimulated by the teacher during the lectures asking students to summarize the concepts explained in the previous lesson. Learning skills are assessed within the different evaluation methods described below.

Organic Chemistry 1, Organic Chemistry 2 and Organic Chemistry 3 (First level in Chemistry).

Definition of supramolecular chemistry. Weak ties. Self-assembled monolayers on surfaces: preparation, structure. Surface analysis techniques for the spectroscopic and physical characterization of 2D-SAM. Modification of 2-D SAM: non-covalent and reversible modification strategies. Covalent modification strategies: Cycloaddition reactions. Alkyne-azide reaction. Metathesis reactions. reactions of carbonyl compounds, Michael reaction. Silylation, and others. Introduction of Nanosciences, Nanotechnologies and Nanochemistry. Self-assembled monolayers in 3 dimensions: nanoparticles. Characteristics of materials in nanometer dimensions. Synthesis of colloids. Characterization techniques of metal nanoparticles. Synthesis of gold nanoparticles protected by an organic monolayer. Characterization of nanoparticles protected by an organic monolayer. Functionalization of 3-D SAM, Mixed Monolayers. Synthesis of nanoparticles of different shapes: synthesis and properties. Applications of gold nanoparticles. Nanolithography. Fullerenes, introduction. Properties, Reactivity of C60. Functionalization reactions of C60. Chemical synthesis of C60. Applications. Carbon nanotubes. Property. Functionalization of CNTs, purification methods. Applications. Organic semiconductor materials: definition, conductivity/conductivity properties. Extrinsic and intrinsic semiconductors. π-extended organic systems. Dyads and multidyads. Introduction to metal-organic frameworks (MOF) and covalent organic frameworks (COF). The teaching contents are consistent with the educational objectives as reported in the Teaching Regulations of the Course of Studies.

T. J. J. Müller, U. H. F. Bunz, Functional Organic Materials. F. A. Carey, R. J. Sundberg, Advanced Organic Chemistry. Material provided by the teacher on MOODLE.

Supramolecular chemistry: definition. Weak bonds: IUPAC definition. Hydrogen bonds, spectroscopic methodologies to study hydrogen bonds. Addition compounds: charge transfer complexes. Host-guest complexes: molecular recognition and cooperativity. Crown ethers, carcerands, cyclophanes, calixarenes, cyclodextrines, rotaxanes and catenanes, molecular motors. Self-assembled monolayers on surfaces: ligands and substrates. Tiolates over gold: general method of preparation, crystal structure of the support. Structure of 2-D SAM on Au(111), description of the sulfur-gold bond. Techniques for the analysis of surfaces and for the physical and spectroscopic characterization of 2-D SAM. Modifications of 2-D SAM: strategies for non-covalent modifictions, LbL, etc. Strategies for the covalent modification. Cycloaddition reactions. Click chemistry: definition and principles. Alkyne-azide cupper catalyzed reaction. Methathesis reactions. Formation of amide bond, esterification, sililation, etc. Reversible modifications of 2-D SAM. Nanolithography. Methodologies to prepare molds by e-beam lithography, photolithography techniques for replicas. Microcontact printing. Di-pen nanolithography. Nanografting and nanoshaving. Introduction to nanoscience, Nanotechnology and Nanochemistry. 3-D self-assembled monolayers: nanoparticles. Features of materials in the nanosize regime. Synthesis of colloids: protocols for the control of the size. Techniques for the characterization of metal nanoparticles: TEM, X-ray techniques, STS. Synthesis of gold nanoparticles protected by organic monolayers, Brust synthesis. X-Ray structures of gold nanoparticles. Characterization of nanoparticles protected by organic monolayers. Synthesis of nanoparticles of different shapes: synthesis and properties of nanorods and their functionalization. Synthesis and properties of silver cubes and gold nanoboxes. Applications of gold nanoparticles as drug vectors and for photodynamic therapy, as contrast agents and as sensors of DNA and proteins. Applications of metal nanoparticles in catalysis. Fullerenes. Properties of C60 and of higher fullerenes. Reactivity of C60. Reactions for the functionalization of C60. Chemical synthesis of C60. Application of C60 in medicine. Carbon nanotubes. Zig-zag, armchair, chiral structures. Properties as metal or semiconductor, mechanical properties. Functionalization of CNT, methods of purification. Applications in the preparation of sensors and transistors. Formation of hybrid materials CNT-metal NPs using covalent bonds or weak interactions. Applications of CNT in medicine. Organic semiconductor materials: definition, properties. Intrinsic aπnd extrinsic materials. π-extended organic compounds. Doped Polyacetylene, charge transfer complexes. Dyads and multidyads with TTF/TCNQ and derivatives. C60 as acceptor in dyads and organic solar cells. Introduction to "metal-organic frameworks, MOF" and "covalent organic frameworks, COF". Characteristics of the reactions to be used for the synthesis, properties of the materials, some examples of applications.

Classroom lessons. Classroom exercises with active participation of the students. Presentation and discussion of a scientific paper.

Understanding of a scientific publication, on topics covered in class, that is presented and discussed during the oral exam. Assessment of the knowledge of the program with oral examination with 3 questions on different topics.