Q1. Knowledge and understanding: At the end of the course the student must demonstrate knowledge of the fundamental principles of the cells and molecules involved in the response mechanisms of the immune system, aimed in particular at the defense against pathogens and the maintenance of tolerance towards the "self ”. Also understand the mechanisms of development of autoimmune and allergic diseases. Understand the modifications of the immune system in the course of senescence, tumor pathologies and in the presence of organ transplants or cell transfusions for therapeutic purposes. Understand the assumptions and modalities of vaccination therapies.
Q2. Ability to apply knowledge and understanding: At the end of the course the student must be able to apply the knowledge acquired in point D1 to foresee possible mechanisms of homeostatic compensation that the body physiologically implements following particular exposures to infectious aggressions or grasp the pathophysiological mechanisms of damage from immune-mediated diseases.
Q3. Making judgements: At the end of the course the student should have sufficient means to judge the physiomolecular and clinical scenarios that are part of the physiological response of the immune type, or in the context of the non-physiological response of the immune system.
Q4. Communication skills: At the end of the course the student must be able to clearly explain the concepts acquired in point D1.
Q5. Learning skills: At the end of the course the student must be able to independently explore the topics covered, and must also be able to transfer the concepts acquired in subsequent courses

PREREQUISITES knowledge of scientific terms PROPEDEUTICITY
teachings of human anatomy, general pathology

PROGRAM
- immunity (concept of)
- innate immunity
- the Complement
- adaptive immunity
- the cells of the immune system
- cytokines
- HLA and antigen presentation
- immunological tolerance
- activation of T and B lymphocytes
- antibodies
- primary and secondary antibody response
- blood groups and antibodies
- monoclonal antibodies
- hypersensitivity reactions
- allergies
- the vaccines
- immunity and aging
- immunity and tumors
- immunodeficiencies

Handbook of Practical and Clinical Immunology, 2e, Vol. II 2nd Edition, Kindle Edition by S.K. Talwar, Gupta (Author) Format: Kindle Edition 2021 The basics of immunology. Pathophysiology of the Immune System (ed 2017) by Abul K. Abbas (Author), Andrew H. Lichtman (Author), Shiv Pillai (Author), Silvano Sozzani (Editor) EDRA Ed.

PROGRAM
- immunity (concept of)
- innate immunity
- the Complement
- adaptive immunity
- the cells of the immune system
- cytokines
- HLA and antigen presentation
- immunological tolerance
- activation of T and B lymphocytes
- antibodies
- primary and secondary antibody response
- blood groups and antibodies
- monoclonal antibodies
- hypersensitivity reactions
- allergies
- the vaccines
- immunity and aging
- immunity and tumors
- immunodeficiencies

-frontal lessons
-Transmission of the recording of the lessons by computer (TEAMS)
- availability for additional instructions or clarifications on the topics covered, via computer or face-to-face interviews

Information on the course contents, verifiable in recording of the lessons on the TEAMS “platform”, teaching material attached to the platform and on Moodle, written by the teacher. Teacher himself available, for information and agreements for interviews, at his university email address, in the “public” domain

written test; questionnaire with 15 multiple choice questions, with a maximum score of 30/30

This course explores topics closely related to one or more goals of the United Nations 2030 Agenda for Sustainable Development (SDGs)