PRINCIPLES OF ORAL PATHOLOGY

[131ME]
a.a. 2025/2026

First semester

Frequency Mandatory

  • 7 CFU
  • 70 hours
  • Italian
  • Trieste
  • Obbligatoria
  • Oral Exam
  • SSD MED/28, MED/50, MED/36
Curricula: COMMON
Syllabus

The course aims for students to acquire:
1) Knowledge and comprehension skills: a thorough knowledge of the pathogenesis, clinical manifestations, treatment and prognosis of diseases of the oro-maxillo-facial district and systemic diseases that may involve the oral district, the radiographic anatomy of periodontal tissues, carrying out the clinical examination and assessing periodontal parameters independently. They will also have to know the basics of the physics of ionising radiation and its interaction with matter, acquire skills, tools and a conscious autonomy of judgement regarding ionising radiation and its effects on biological tissues, learn the basic principles and indications of orthopantomography and dentascan tc, reason according to the specific logic of the discipline of radiology. They should also be familiar with disease-fighting mechanisms, examining the coordinated interactions between different cellular systems in the development of inflammation related to protection against infection. Become familiar with the basis and integrated functioning of acquired and adaptive immunity in different cellular and molecular functions, understand the concept of self and non-self and the basis of autoimmune diseases. Finally, to study the functions of the immune system associated with the development of neoplastic cells.
2) Knowledge and understanding applied: The student must show that he/she has acquired skills, tools and an informed autonomy of judgement in relation to the pathologies treated.
3) Autonomy of judgement: these notions will be the fundamental background for understanding the pathologies of the oral cavity in their various clinical manifestations (odontogenic and non-odontogenic infections of the oral cavity, periodontal pathologies, oral cavity tumours, etc.)
4) Communication skills, getting used to the classroom presentation of concepts required by the lecturer, in a stimulating and interactive teaching environment. Students will always be urged to bear in mind the need for scientifically rigorous exposition and communication with colleagues and simple, yet comprehensive, communication with patients and their families. They will be stimulated to express themselves in correct and essential language.
5) Ability to learn: during the lectures, reference will mainly be made to the texts recommended by the lecturers of the individual modules, although students will be urged to consult several of them, citing the sources of the information presented. The topics covered will always be approached from different points of view, so that the student can form a clear and complete opinion of them.

In-depth knowledge of biology and genetics, histology, human and dental anatomy, physiology, general microbiology, pathology and general hygiene, pathological anatomy.
In order to take the special odontostomatological pathology module, the student must have passed the following integrated courses included in the syllabus: BASIC BIOMEDICAL SCIENCES, HUMAN MORPHOLOGICAL SCIENCES AND PHYSIOLOGY, ETHIOPATHOGENESIS OF DISEASES.

SPECIAL ODONTOSTOMATOLOGIC PATHOLOGY
The contents of the course concern the etiopathogenesis, the clinical and instrumental diagnostic pathways and the therapy of oral diseases with reactive, infectious, autoimmune and neoplastic etiologies.
It will also be analyzed the main pathologies affecting other districts and which can foster the presence of oral manifestations (dermatological, rheumatological, metabolic, solid neoplastic and haematological diseases), as well as oral lesions induced by topical and systemic pharmacological treatments.

TECHNIQUES OF SEMIOTICS AND MONITORING OF ORAL CAVITY 2
Periodontology
Evaluate the periodontal radiographic images
Know and classify bone defects
Know and classify soft tissue defects

DENTAL RADIOLOGY 1
1. Introduction
2. X ray physical principles
3. Interaction between X ray and matter
4. Radiobiology
5. Radioprotection
6. Ultrasound
7. Computer Tomography
8. CT Dentascan
9. Orthopantomography

DENTAL RADIOLOGY 2
Special part:
1. Radiology of caries
2. Odontogenic and non-odontogenic cysts
3. Pulp and Periodontal Pathology
4. Odontogenic Trauma
5. Maxillary trauma
6. Inflammatory Pathology
7. Expansive pathology

IMMUNOLOGY APPLIED TO ORAL PATHOLOGY
- The immune system and its components.
- The inflammatory response
- The Complement: activation and functions
- Humoral and infocyte immunity B
- T lymphocytes
- activation of the immune system against infectious agents
- activity of the immune system in the oral cavity
- Autoimmunity
- Immune hypersensitivity
- immune deficiencies

SPECIAL ODONTOSTOMATOLOGICAL PATHOLOGY
SIPMO Pathology and Oral Medicine
Edra publisher. Authors: Biasotto, Campisi, Lodi, Lo Muzio, Mignogna, Montebugnoli, Sardella

SEMEIOTIC TECHNIQUES AND MONITORING OF THE ORAL CAVITY 2
Clinical periodontology and oral implantology - 2017 Edition - 2 indivisible volumes set by Lindhe - Nicklaus - Lang - 2016 -

ODONTOSTOMATOLOGICAL RADIOLOGY 1 and 2
CITTADINI G.: Manual of Clinical Radiology - Ed. ECIG

IMMUNOLOGY APPLIED TO ORAL PATHOLOGY
Microbiology and Immunology of the Oral Cavity by Lamont - Burne - Lantz – LeBlanc; lecture notes

SPECIAL ODONTOSTOMATOLOGICAL PATHOLOGY
- Classification and principles of pathophysiology of chronic orofacial pain
- Trigeminal neuralgia, BMS, PIFP, dysgeusia
- Bacterial, fungal and fungal infections
- Bullous and autoimmune diseases
- Orofacial vasculitis
- Pigmented lesions of the oral mucosa
- Potentially malignant disorders of the oral cavity
- Oral carcinoma and other malignant neoplasms of the oral cavity
- Odontogenic and non-dontogenic jaw diseases
- Anatomical and para-physiological variants
- Benign and reactive neoformations of the oral mucosa

SEMEIOTIC TECHNIQUES AND MONITORING OF THE ORAL CAVITY 2
Radiographic anatomy of periodontal tissues
Conducting the clinical examination and assessing periodontal parameters

ODONTOSTOMATOLOGICAL RADIOLOGY 1 and 2
General part:
1. Introduction
2. The physics of X-rays
3. The interaction of X-rays with matter
4. Radiobiology
5. Radiation protection
6. Ultrasound
7. Computed tomography
8. CT Dentascan
9. Orthopantomography

Special part:
1. Caries radiology
2. Odontogenic and non-odontogenic cysts
3. Pulp pathology and periodontal disease
4. Odontogenic trauma
5. Maxillary trauma
6. Phlogistic pathology
7. Expansive pathology

IMMUNOLOGY APPLIED TO ORAL PATHOLOGY
- The immune system and its components
- Immune homeostasis
- The inflammatory response
- The complement: activation and functions
- Humoral immunity and B lymphocytes
- T lymphocytes
- activation of the immune system against infectious agents
- Immune system activity in the oral cavity
- Autoimmunity
- Immunology of tumours
- Immune hypersensitivities

Conventional lectures.
Any changes to the methods described herein, which may be necessary to ensure the application of COVID19 emergency-related safety protocols, will be communicated on the DSM, Course of Study and teaching websites.

Lessons will be recorded and stored on Teams platform.

Students must sit the individual partial examinations on the dates scheduled in the Degree Course examination calendar. In particular, the performance of partial examinations, the results of which must be published using the "Partial examinations" IT tool provided by the Esse3 platform, will be recorded in a single final appeal in which the Commission proceeds to verify the overall results of the integrated course and to record them. The student must register for the online appeal of the partial examination on ESSE3. The grade for the partial examination will be held valid until the extraordinary session of the academic year in question. In order to pass the examination relating to the course, the student must obtain a mark of ≥ 18 in each of the partial examinations; he/she may not reject the result of the partial examination, but only the grade for the entire integrated course, in which case he/she must repeat all the partial examinations.
The final mark for the integrated course examination is derived from the weighted average, thus weighted on the CFUs of each module, obtained in the individual partial tests. For the purposes of defining the average, any honours obtained in the partial examinations will be assigned a value of 1 point, i.e. a mark of 30 with honours in the partial examinations corresponds numerically to a mark of 31. In order to assign honours to the final examination mark, it will be necessary for the weighted average obtained by the student in the partial examinations relating to the various modules to be >30,5.
For all modules of the integrated course, the examination is based on the entire course programme.
Verification of the knowledge acquired, for course 131ME-1, 131ME-2 and 131ME-5 will be by means of a written examination with multiple-choice and open-ended questions. For modules 131ME-3 and 131ME-4 the student's assessment will be by means of an oral examination with questions designed to assess the student's knowledge and reasoning ability.
The evaluation grid adopted is as follows
- Excellent (30 - 30 cum laude): very good knowledge of the subject matter, very good ownership of language, very good analytical ability; the student is able to apply theoretical knowledge brilliantly.
- Very good (27 - 29): good knowledge of the subject matter, remarkable command of language, good analytical ability; the student is able to apply the theoretical knowledge correctly.
- Good (24-26): good knowledge of the main topics, fair command of language; the student shows an adequate ability to apply theoretical knowledge.
- Satisfactory (21-23): the student does not show full mastery of the main topics of the course, although he/she possesses the fundamental knowledge; however, he/she shows satisfactory language skills and sufficient ability to apply theoretical knowledge.
- Sufficient (18-20): minimal knowledge of the main teaching topics and technical language, limited ability to apply theoretical knowledge adequately.
- Insufficient: the student does not possess an acceptable knowledge of the content of the various topics of the syllabus.

This course explores topics closely related to one or more goals of the United Nations 2030 Agenda for Sustainable Development (SDGs)

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